Our Approach

The REDI-NET consortium is envisioned as a long-term, phased initiative that serves as a global Center of Excellence to leverage, coordinate and integrate pre-existing and novel real-time xenosurveillance efforts to optimize pathogen discovery and to provide a one-stop-shop for actionable pathogen intelligence for decision-makers. 

The seamless integration of environmental parameters and bio-/xeno-surveillance pathogen data into a newly developed REDI-NET data warehouse will facilitate the development of a comprehensive data analysis pipeline.

REDI-NET Phased Approach

Phase I (Completed)

Phase I leverages existing DoD, academic, and civilian partnerships and provides a solid foundation of excellence to build a unique electronically merged data pipeline (e-MERGE) and REDI-NET pathogen spillover alert dashboard, supported by Gold standard reach-back labs with field-ready hi-tech SOPs for standardized remote DNA-based pathogen detection. The REDI-NET alert dashboard, with built-in functionality and data quality assurance for downstream use in mathematical modeling, will inform of changes with the relative portions on the contributory components of each pathogen with regard to baseline data, and generate prior warning of potential spillover events in real-time, initiating response and mitigating risks to global citizens and deployed warfighters.

A central function of the e-MERGE analysis pipeline developed to include novel risk maps and models.

Phase II (Currently active)

Phase II will expand the sampling frame of the established complementary diagnostic workflow developed under Phase I into new ecologies or terrain. Phase II will expand the REDI-NET pathogen portfolio to include opportunistic vDNA outputs and an enhanced data warehouse, develop an actionable workflow for early pathogen detection by remote forward-facing laboratories using the e-MERGE pipeline, and transfer knowledge of REDI-NET technology and processes to key DoD stakeholders.

Sampling expansion will serve to establish new mobile laboratories, for further reach of threat characterization, as well as, verify the correctness of Phase I threat forecast models through new/updated parameters to confirm emergence of targeted vectors and pathogens.

Redi Net P2 Study Design

Phase III (proposed)

Phase III will focus on establishing new regional satellite laboratories (Bronze) to expand upon Phase I and Phase II outputs and integrate new remote data acquisition technologies to assess emerging disease threats. Phase III will expand the REDI-NET pathogen portfolio to include active vDNA sampling and field metadata collection; establish, maintain, and expand REDI-NET active surveillance of iDNA and eDNA across varied ecologies and the Geographical Combatant Commands (GCCs) for broad spectrum pathogen detection using established SOPs; and readiness for roll-out of the REDI-NET platform to Senior DoD Officials in six GCCs and the AFHSC-GEIS partner network.

As data accrual improves, strategic sampling will become model-driven.

Phase IV (proposed in 2 separate fiscal years)

Phase IV will focus on rolling out the REDI-NET e-MERGE pipeline to Global Combatant Commands to assess emerging disease threats and ensure robust Force Health Protection and Force Readiness.